Yield modelling and yield enhancement for FPGAs using fault tolerance schemes

Published versio

Numerical Investigation of the Influence of Span-wise Force Variation in Circular Cylinders Undergoing Vortex Induced Vibrations at High Reynolds Number

The focus of this research is on the development of a new approach for simulating vortex induced vibrations on marine risers at high Reynolds numbers. This method considers the span-wise variation of the lift and drag forces, and determines the moment acting on the cylinder. The predicted motion then consists of a rotational component to accompany the traditional cross-stream and stream-wise translations normally associated with vortex induced vibrations. This was accomplished by describing the motion of the cylinder using a set of springs and dampers. A moment acting on the cylinder causes the springs on one end to compress, and stretch on the other, thus rotating the cylinder. A Large Eddy Simulation (LES) computational fluid dynamics code running on 16 3Ghz processors was used to calculate the unsteady flow and at each time step the hydrodynamic forces acting on the cylinder were calculated in a separate routine based on the pressure distribution around the cylinder. This information was then used to solve two second-order ordinary differential equations, which gave the velocity and displacement of the cylinder in cross-flow and rotational planes. This information was transferred back to the code where the cylinder was displaced and another cycle of calculations was started. The simulated results showed that the correlation length was higher for a cylinder subject to pure translation compared to a cylinder free to translate and rotate in the cross-stream direction. This has implications for current numerical and experimental techniques since it has been traditionally assumed that the flow around a circular cylinder becomes two-dimensional during vortex induced vibrations. Consequently, empirical,numerical and experimental models have generally only considered cross stream and/or stream-wise translation. The extent to which the experimental apparatus or harmonic model may have influenced the behavior of the riser by eliminating span-wise amplitude variation is important information that should be considered for future riser designs

Causas más frecuentes de anemia en una población adulta de la ciudad de La Rioja.

La anemia constituye un problema importante de la salud pública que afecta tanto a niños como adultos. Existen múltiples causas que pueden desarrollarla, por lo que su estudio constituye una tarea ardua y a veces de difícil diagnóstico. El presente trabajo se enfoca en conocer las causas más frecuentes de anemia en la población adulta riojana (18–80 años) que acude a la interconsulta hematológica ambulatoria, en un servicio hematológico privado. A través de la revisión de historias clínicas (362), del periodo de Julio del 2008 a Julio del 2011, se estableció que la prevalecía de anemia fue mayor en mujeres (69%) que en hombres (19%). Los resultados obtenidos sugieren que la anemia de la enfermedad crónica y la deficiencia de hierro son las causas más comunes y frecuentes en la población adulta. Estadísticamente se estableció una significancia clínica, p-valor 0.001 (á= 0.05), entre las enfermedades subyacentes de un paciente y la edad del mismo, como factores que contribuyen al desarrollo de un síndrome anémico.Most common causes of anemia in an adult population City of La Rioja.AbstractAnaemia is a major problem of public health that affects both children and adults. There are many causes that can develop, so their study is an arduous and sometimes difficult to diagnose. This paper focuses on knowing the most common causes of anemia in adults Rioja (18-80 years) who comes to the outpatient hematology interconsultation in private hematology service. Through medical record review (362), the period of July 2008 to July 2011, it was established that the prevalence of anemia was higher in women (69%) than men (19%). The results suggest that anemia of chronic disease and iron deficiency are the most common and frequent in the adult population. Statistically established clinical significance, p-value 0.001 (á = 0.05), between a patient's underlying disease and age of the same, as factors contributing to the development of an anemic syndrome.Key words: Anemia; Adult; Causes; Multifactorieda

Reconfiguration and Fine-Grained Redundancy for Fault Tolerance in FPGAs

Published versio

The inflammatory microenvironment in colorectal neoplasia

Peer reviewedPublisher PD

ILC3 function as a double-edged sword in inflammatory bowel diseases

Inflammatory bowel diseases (IBD), composed mainly of Crohn’s disease (CD) and ulcerative colitis (UC), are strongly implicated in the development of intestinal inflammation lesions. Its exact etiology and pathogenesis are still undetermined. Recently accumulating evidence supports that group 3 innate lymphoid cells (ILC3) are responsible for gastrointestinal mucosal homeostasis through moderate generation of IL-22, IL-17, and GM-CSF in the physiological state. ILC3 contribute to the progression and aggravation of IBD while both IL-22 and IL-17, along with IFN-γ, are overexpressed by the dysregulation of NCR− ILC3 or NCR+ ILC3 function and the bias of NCR+ ILC3 towards ILC1 as well as regulatory ILC dysfunction in the pathological state. Herein, we feature the group 3 innate lymphoid cells’ development, biological function, maintenance of gut homeostasis, mediation of IBD occurrence, and potential application to IBD therapy